Cancer is the leading cause of death by disease in children and adolescents in the US
Brain and Central Nervous System tumors are the most common cancer in children 0-14 years in the US
There are more than 140 different types of brain tumors, many with their own multitude of subtypes
Childhood cancer survivors are at significant risk for secondary cancers later in life
More than 28,000 children (0-19 years of age) are estimated to be living with a brain tumor in the US
About 4,600 children and teenagers are diagnosed with a primary brain or central nervous system tumor every year. That's 13 new cases a day
Between 1998 and 2014, there were 78 investigational brain tumor drugs that entered the clinical trial evaluation process-75 failed. That is a 25:1 failure ratio in developing new brain tumor treatments over the past 2 decades
Brain tumors affect all races, ages, gender, and ethnicities
All types of childhood cancer combined receive less than 4% of the US Federal funding for cancer research
More than 40,000 children undergo treatment for cancer each year
Childhood cancer does not discriminate, sparing no ethnic group, socioeconomic class or geographic region
Brain tumors are often located in the control center for thought, memory, sensation, emotion, vision and movement, and therefore, their effect can be particularly devastating
The overall mortality rate of pediatric cancer has decreased in past 20 years, but deaths from brain and spinal cord tumors have increased from 18% to 30%
Among the chemotherapy side effects are hair loss, skin problems, nausea, vomiting, diarrhea, constipation, changes in taste, fatigue, mouth sores, seizures, hearing loss, kidney and liver problems, and reduction of platelets, red cells, or white cells in the blood. Some are temporary others maybe permanent
Brain tumors have the highest per-patient initial cost of care for any cancer group
The causes of most pediatric cancer remain a mystery and cannot be prevented
Many brain tumor survivors require physical, cognitive and rehabilitation services to allow them to return to tasks of everyday life
Pediatric brain tumors are different from those in adults and are often treated differently
Pediatric brain tumors aren't like those in adults. Children's brain tumors require specific research and different treatments
Despite the amount of brain tumors, and their devastating prognosis, there have only been 4 FDA approved drugs-and 1 device-to treat brain tumors in the past 30 years
The terms "benign" and "malignant" as usually applied to tumors are not as useful when describing brain tumors, because the brain and skull comprise a "box" of a fixed size, even "benign" or slow-growing tumors can cause serious problems or eventual death if they develop in an area where complete surgical removal is not possible
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